Independent Scientific Validation of The Fountain of Youth Lifestyle Tripeptide Collagen
The Fountain of Youth Lifestyle (FoYL) Tripeptide Collagen has been independently tested by a leading European university using pharmaceutical laboratory models.
In-Vitro & In-Situ Studies
FoYL’s tripeptide collagen has undergone independent, third-party, pharmaceutical laboratory testing by the University of Studies of Milan
to evaluate not just composition, but functional biological performance — something never done before for collagen ingredients.
The independent studies were conducted by:
Università degli Studi di Milano (University of Studies of Milan) —
Dipartimento di Scienze Farmaceutiche (Department of Pharmaceutical Sciences) (DiSFaRM)
Final Scientific Report Date: 27 June 2025
Click Here
to view a synopsis of the clinical trial results (opens in a new window).
What These Studies Confirm — And Why It Matters
Independent laboratory testing demonstrated that FoYL’s tripeptide collagen is fundamentally different from standard or hydrolysed collagen products.
Rather than acting solely as a source of amino acids, FoYL’s ultra-low molecular weight tripeptide collagen was shown to behave as a
bioactive peptide system, interacting with key metabolic and vascular pathways under controlled laboratory conditions.
Key Outcomes from the Independent Testing
Up to 5× Higher Predicted Bioactivity
Advanced peptide mapping showed that FoYL’s tripeptide collagen exhibits up to five times greater predicted biological activity
compared with conventional collagen peptides.
What this means for you:
More of the collagen you consume is biologically “active”, not just digested and discarded.
Precision Peptides for Superior Absorption
- 300–500 Dalton molecular weight
- Over 80% tripeptides
This size range aligns with the optimal zone for collagen peptide absorption and signalling, allowing peptides to be rapidly absorbed while retaining their functional activity.
What this means for you:
Your body can absorb and use this collagen more efficiently than standard, larger collagen peptides.
Supports Natural Metabolic Signalling
Laboratory testing showed that FoYL’s tripeptide collagen:
- Stimulated pathways involved in natural satiety signalling
- Helped maintain balanced post-meal metabolic responses
- Demonstrated activity at realistic daily intake levels
What this means for you:
Support for metabolic balance — not through stimulants or drugs, but by working with your body’s own signalling systems.
Supports Healthy Circulation Pathways
The studies also demonstrated interaction with enzyme systems involved in:
- Vascular relaxation
- Blood flow regulation
What this means for you:
FoYL collagen supports whole-body wellbeing, not just skin, hair, or joints.
Proven to Remain Active in the Gut
Importantly, FoYL’s tripeptide collagen retained biological activity in human intestinal cell models (in-situ testing).
Most collagen products are never tested this way or to this level.
What this means for you:
This collagen doesn’t just look good on paper — it remains active where absorption actually occurs.
Gentle & Well Tolerated
- High cell viability observed in testing
- Confirms compatibility under laboratory conditions
What this means for you:
Designed for daily use as part of a long-term wellness routine.
Why This Sets FoYL Collagen Apart
Most collagen products rely on:
- Generic hydrolysed collagen
- Amino-acid profiles
- Broad, non-specific claims
FoYL’s collagen is supported by independent university-led testing demonstrating:
- Higher bioactivity
- Better absorption potential
- Functional metabolic and vascular relevance
This positions FoYL collagen as a next-generation, precision-designed collagen, not a commodity protein powder.
The Fountain of Youth Lifestyle Tripeptide Collagen.
The Next Evolution of Collagen.
Reference
Independent scientific evaluation conducted by:
Università degli Studi di Milano (University of Studies of Milan) —
Dipartimento di Scienze Farmaceutiche (Department of Pharmaceutical Sciences) (DiSFaRM)
Final report dated 27.06.2025
Additional Scientific Studies
Please Note: Not all related to Tripeptide Collagen
Summaries
| # |
Study & model |
What they measured |
Direction of the main result |
| 1 |
Inoue 2016 – 8-week DB-RCT, 56 women, 5 g/day bovine HC |
Corneometer skin hydration, Cutometer elasticity, fringe-projection wrinkle depth |
↑ Hydration (+7–12%), ↑ elasticity (+4–9%), ↓ wrinkle depth (−8%) vs placebo |
| 2 |
Ohara 2007 – single-dose crossover PK, 5 men, 10 g bovine HC |
Plasma levels of Hyp-di/tri-peptides |
Peaks of 20–60 nmol mL⁻¹ Pro-Hyp / Hyp-Gly at 1–2 h post-dose (none at baseline) |
| 3 |
Iwai 2005 – single-dose PK, 5 volunteers, 10 g porcine/bovine HC |
Identification of intact tripeptides in serum |
First evidence of Pro-Hyp appearance in human blood after oral collagen |
| 4 |
Ichikawa 2010 – dose-escalation PK, 4 volunteers |
Dose-response of plasma Hyp-peptides (30–385 mg kg⁻¹) |
Clear, linear ↑ in peptide Cmax with higher doses (6 → 33 nmol mL⁻¹) |
| 5 |
Watanabe-Kamiyama 2010 – ovariectomised-rat model, 4 wks LMW bovine HC |
Femoral bone organic content & BMC |
↑ Bone organic matter and BMC (+7%) vs controls |
| 6 |
Yamamoto 2016 – human crossover, 9 subjects, tripeptide-enriched CTP vs generic HC |
Plasma & urinary Gly-Pro-Hyp / Pro-Hyp |
Higher and longer-lasting peptide levels with CTP-50; magnitude proportional to tripeptide dose |
| 7 |
Proksch 2014 – 114 women, 2.5 g VERISOL® for 8 wks |
3-D stereo wrinkle volume & dermal biopsies |
−20% eye-wrinkle volume; +65% procollagen-I vs placebo (p < 0.05) |
| 8 |
Proksch 2013 – 69 women, 2.5 / 5 g collagen peptides for 8 wks |
Cutometer elasticity (R2) |
+15% elasticity at both doses; effect persisted 4 wks after stopping |
| 9 |
Song 2013 (Kim BJ) – 64 adults, 3 g collagen tripeptide, 12 wks |
Hydration & elasticity vs control |
+28% hydration, +19% elasticity; both significant vs control |
| 10 |
Hexsel 2017 – 25 women, 2.5 g VERISOL®, 24 wks (open-label) |
Nail growth rate & brittleness |
+12% growth rate, −42% cracked/brittle nails; 64% “overall improvement” by physician assessment |